Let’s Design Your Targeted Sequencing Assays
Accel-Amplicon Custom NGS Panels offer a completely curated, targeted NGS workflow to rapidly and precisely interrogate genomic targets relevant to your research. This approach is ideal as a follow-up to whole genome or exome sequencing studies, as well as diving deep into specific biological pathways.
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Accelerating variant discovery in challenging biological samples
Accel-Amplicon Custom NGS Panels generate highly multiplexed, targeted PCR libraries that are compatible with both Illumina® and Ion Torrent™ sequencing platforms. The unique single-tube design is also compatible with most sample types, including limited or degraded samples such as FFPE and cfDNA samples.
Tailored to meet your specific needs, Accel-Amplicon Custom NGS Panels can be customized to include coverage of both clinically-relevant hotspot loci and regions of contiguous coverage, as well as Sample_ID targets spiked-in at a low percentage (2-4% of reads). This allows for somatic mutation detection using high depth of coverage and sample identification using low coverage depth of germline targets.
The Accel-Amplicon workflow provides a fast, single-tube approach resulting in a < 2-hour start-to-finish procedure, including hands-on time.
The single-tube workflow includes two brief incubations to generate the multiplex amplicon targets and add a unique combination of Illumina-compatible indexed adapters, creating up to 96 uniquely-indexed libraries for multiplexing on a single sequencing run.
Eliminate the variant valling bottleneck
In partnership with Genialis, Swift provides basic and clinical researchers’ with a streamlined data analysis solution that integrates alignment, primer trimming, QC and variant calling into one, simple pipeline.
Please contact us for more details.